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Copper & Skin Peptide Research

GHK-Cu Research

GHK-Cu is a naturally occurring copper-binding peptide investigated in extracellular-matrix, fibroblast and skin biology.

Evidence status

Human cosmetic evidence: less extensive than many online claims suggest.

What is GHK-Cu?

GHK-Cu is a naturally occurring copper complex formed when glycyl-L-histidyl-L-lysine binds copper ions. Its interaction with copper and extracellular-matrix biology has made it interesting to researchers studying skin, fibroblasts, collagen and tissue remodelling.

What is GHK-Cu being studied for?

Laboratory research has examined GHK-Cu in relation to fibroblast biology, collagen production and turnover, glycosaminoglycans, metalloproteinases, extracellular-matrix remodelling and skin biology.

GHK vs GHK-Cu

GHK is the three-amino-acid peptide itself. GHK-Cu is the copper-bound complex. They are closely related but chemically distinct forms.

Evidence status

Mechanistic and cellular evidence is substantial. Human cosmetic evidence is less extensive than many online claims suggest.